Bone morphogenic protein-2 (BMP-2) protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues. BMP-2 protein may play an important role in the progression of glioma.

Product Name Recombinant human bone morphogenic protein-2 (BMP-2)
Biological Activity Measured by its ability to induce alkaline phosphatase production by C2C12 mouse myoblast, ED₅₀ = 0.625 µg/ml. (The ED₅₀ for this effect is typically 0.28~0.84 µg/ml.)
Purity >98% as determined by SDS-PAGE analysis
Endotoxin Level Please contact us for more information
Expression System E. coli
Accession P12643
Protein Length Full length protein (mature form)
Species Human (Alpaca, Cow, Dog, Gelatin Microparticles, Human, Monkey, Mouse, Rabbit, Rat)
Predicted Molecular Weight The recombinant human BMP2 consists of 114 amino acids and has a predicted molecular mass of 13 kDa. It migrates as an approximately 13 & 26 kDa band in SDS-PAGE under reducing conditions, corresponding to the monomer and homodimer.
Amino Acids 283 to 396
Product Form Lyophilized
Stability and Storage Shipped on Dry Ice. Store at -20°C for 6 months. Avoid freeze-thaw cycle.

Recombinant Human Bone Morphogenic Protein-2 (BMP-2)

  • Cat. No.: CRP-001-0XXXX

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