Bone morphogenic protein-2 (BMP-2) protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues. BMP-2 protein may play an important role in the progression of glioma.

Specification
Product Name	Recombinant human bone morphogenic protein-2 (BMP-2)
Biological Activity	Measured by its ability to induce alkaline phosphatase production by C2C12 mouse myoblast, ED₅₀ = 0.625 µg/ml. (The ED₅₀ for this effect is typically 0.28~0.84 µg/ml.)
Purity	>98% as determined by SDS-PAGE analysis
Endotoxin Level	Please contact us for more information
Expression System	E. coli
Accession	P12643
Protein Length	Full length protein (mature form)
Species	Human (Alpaca, Cow, Dog, Gelatin Microparticles, Human, Monkey, Mouse, Rabbit, Rat)
Predicted Molecular Weight	The recombinant human BMP2 consists of 114 amino acids and has a predicted molecular mass of 13 kDa. It migrates as an approximately 13 & 26 kDa band in SDS-PAGE under reducing conditions, corresponding to the monomer and homodimer.
Amino Acids	283 to 396
Product Form	Lyophilized
Stability and Storage	Shipped on Dry Ice. Store at -20°C for 6 months. Avoid freeze-thaw cycle.

Recombinant Human Bone Morphogenic Protein-2 (BMP-2)

Cat. No.: CRP-001-0XXXX

Available Options

Pack Size

10 µg (Cat. No. CRP-001-00010)

50 µg (Cat. No. CRP-001-00050)

100 µg (Cat. No. CRP-001-00100)

1 mg (Cat. No. CRP-001-01000)

Qty